EMD-20667
Biochemical and structural analysis of the Neurofibromin (NF1) protein reveals high-affinity dimer formation
EMD-20667
Single-particle18.5 Å
Deposition: 30/08/2019Map released: 08/01/2020
Last modified: 05/02/2020
Sample Organism:
Homo sapiens
Sample: Neurofibromin is the protein product of the NF1 gene Human NF1 isoform 2 (NM_000267.3).
Deposition Authors: Juneja P, Sherekar M, Esposito D, Han SW, Ghirlando R, Messing S, Drew M, Niel OH, Stanley C, Bhowmik D, Ramanathan A, Subramaniam S, Nissley D, Gillette W, McCormick F
Sample: Neurofibromin is the protein product of the NF1 gene Human NF1 isoform 2 (NM_000267.3).
Deposition Authors: Juneja P, Sherekar M, Esposito D, Han SW, Ghirlando R, Messing S, Drew M, Niel OH, Stanley C, Bhowmik D, Ramanathan A, Subramaniam S, Nissley D, Gillette W, McCormick F
Biochemical and structural analyses reveal that the tumor suppressor neurofibromin (NF1) forms a high-affinity dimer.
Sherekar M 
,
Han SW,
Ghirlando R ,
Messing S,
Drew M,
Rabara D,
Waybright T,
Juneja P ,
O'Neill H ,
Stanley CB ,
Bhowmik D,
Ramanathan A,
Subramaniam S ,
Nissley DV,
Gillette W ,
McCormick F,
Esposito D
(2020) J. Biol. Chem. , 295 , 1105 - 1119
,
Han SW,
Ghirlando R ,
Messing S,
Drew M,
Rabara D,
Waybright T,
Juneja P ,
O'Neill H ,
Stanley CB ,
Bhowmik D,
Ramanathan A,
Subramaniam S ,
Nissley DV,
Gillette W ,
McCormick F,
Esposito D
(2020) J. Biol. Chem. , 295 , 1105 - 1119