EMD-20857

Single-particle
3.71 Å
EMD-20857
3D View Gallery
Deposition: 22/10/2019
Map released: 29/04/2020
Last modified: 29/07/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-20857
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6ur8 summary report (pdf.gz) Map and 6ur8 FULL report (pdf.gz)
EMICSS annotations (xml)

CryoEM structure of human alpha4beta2 nicotinic acetylcholine receptor in complex with varenicline

EMD-20857

Single-particle
3.71 Å
EMD-20857
3D View Gallery
Deposition: 22/10/2019
Map released: 29/04/2020
Last modified: 29/07/2020
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: human alpha4beta2 nicotinic acetylcholine receptor in complex fab fragments and bound to varenicline
Fitted models: 6ur8

Deposition Authors: Alvarez FJD, Mukherjee S, Han S, Ammirati M, Kossiakoff AA
Synthetic antibodies against BRIL as universal fiducial marks for single-particle cryoEM structure determination of membrane proteins.
Mukherjee S, Erramilli SK , Ammirati M, Alvarez FJD, Fennell KF, Purdy MD, Skrobek BM , Radziwon K, Coukos J , Kang Y, Dutka P , Gao X, Qiu X, Yeager M, Eric Xu H, Han S , Kossiakoff AA
(2020) Nat Commun , 11 , 1598 - 1598
PUBMED: 32221310
DOI: doi:10.1038/s41467-020-15363-0
ISSN: 2041-1723