EMD-22947
Negative stain electron microscopy reconstruction of non-neutralizing NTD-directed antibody Fab in complex with SARS-CoV-2 spike ectodomain in the 1-RBD-up state
EMD-22947
Single-particle17.5 Å
Deposition: 04/11/2020Map released: 18/11/2020
Last modified: 01/09/2021
Sample Organism:
Severe acute respiratory syndrome coronavirus 2
Sample: Complex of RBD-directed Fab DH1042 with hexapro SARS-CoV-2 spike ectodomain
Deposition Authors: Edwards RJ, Mansouri K
Sample: Complex of RBD-directed Fab DH1042 with hexapro SARS-CoV-2 spike ectodomain
Deposition Authors: Edwards RJ, Mansouri K
In vitro and in vivo functions of SARS-CoV-2 infection-enhancing and neutralizing antibodies.
Li D,
Edwards RJ 
,
Manne K,
Martinez DR,
Schafer A,
Alam SM,
Wiehe K,
Lu X,
Parks R,
Sutherland LL,
McDanal C,
Perez LG,
Mansouri K ,
Gobeil SMC,
Janowska K,
Stalls V,
Kopp M,
Cai F,
Lee E,
Foulger A,
Hernandez GE,
Sanzone A,
Tilahun K ,
Jiang C,
Tse LV,
Bock KW,
Minai M,
Nagata BM,
Cronin K,
Gee-Lai V,
Deyton M,
Barr M,
Von Holle T,
Macintyre AN,
Stover E,
Feldman J,
Hauser BM ,
Caradonna TM ,
Scobey TD,
Rountree W,
Wang Y,
Moody MA,
Cain DW,
DeMarco CT,
Denny TN,
Woods CW,
Petzold EW,
Schmidt AG,
Teng IT,
Zhou T,
Kwong PD,
Mascola JR,
Graham BS,
Moore IN,
Seder R,
Andersen H,
Lewis MG,
Montefiori DC,
Sempowski GD ,
Baric RS,
Acharya P,
Haynes BF,
Saunders KO
(2021) Cell , 184 , 4203 - 4219.e32
,
Manne K,
Martinez DR,
Schafer A,
Alam SM,
Wiehe K,
Lu X,
Parks R,
Sutherland LL,
McDanal C,
Perez LG,
Mansouri K ,
Gobeil SMC,
Janowska K,
Stalls V,
Kopp M,
Cai F,
Lee E,
Foulger A,
Hernandez GE,
Sanzone A,
Tilahun K ,
Jiang C,
Tse LV,
Bock KW,
Minai M,
Nagata BM,
Cronin K,
Gee-Lai V,
Deyton M,
Barr M,
Von Holle T,
Macintyre AN,
Stover E,
Feldman J,
Hauser BM ,
Caradonna TM ,
Scobey TD,
Rountree W,
Wang Y,
Moody MA,
Cain DW,
DeMarco CT,
Denny TN,
Woods CW,
Petzold EW,
Schmidt AG,
Teng IT,
Zhou T,
Kwong PD,
Mascola JR,
Graham BS,
Moore IN,
Seder R,
Andersen H,
Lewis MG,
Montefiori DC,
Sempowski GD ,
Baric RS,
Acharya P,
Haynes BF,
Saunders KO
(2021) Cell , 184 , 4203 - 4219.e32