EMD-23153
Cryo-electron microscopy local refinement of antibody DH898.1 Fab-dimer bound to glycans 332, 392, and 396 of HIV Env CH848 10.17 SOSIP trimer
EMD-23153
Single-particle7.0 Å
Deposition: 17/12/2020Map released: 03/03/2021
Last modified: 09/06/2021
Sample Organism:
Macaca mulatta,
Human immunodeficiency virus 1
Sample: Antibody DH898.1 Fab-dimer bound to glycans 332, 392, and 396 of HIV Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 trimer
Deposition Authors: Edwards RJ, Acharya P
Sample: Antibody DH898.1 Fab-dimer bound to glycans 332, 392, and 396 of HIV Env CH848.3.D0949.10.17chim.6R.DS.SOSIP.664 trimer
Deposition Authors: Edwards RJ, Acharya P
Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Williams WB,
Meyerhoff RR 
,
Edwards RJ ,
Li H,
Manne K ,
Nicely NI ,
Henderson R,
Zhou Y ,
Janowska K,
Mansouri K ,
Gobeil S,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V ,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T ,
Sempowski GD ,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G ,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P ,
Haynes BF
(2021) Cell , 184 , 2955 - 2972.e25
,
Edwards RJ ,
Li H,
Manne K ,
Nicely NI ,
Henderson R,
Zhou Y ,
Janowska K,
Mansouri K ,
Gobeil S,
Evangelous T,
Hora B,
Berry M,
Abuahmad AY,
Sprenz J,
Deyton M,
Stalls V ,
Kopp M,
Hsu AL,
Borgnia MJ,
Stewart-Jones GBE,
Lee MS,
Bronkema N,
Moody MA,
Wiehe K,
Bradley T,
Alam SM,
Parks RJ,
Foulger A,
Oguin T ,
Sempowski GD ,
Bonsignori M,
LaBranche CC,
Montefiori DC,
Seaman M,
Santra S,
Perfect J,
Francica JR,
Lynn GM,
Aussedat B,
Walkowicz WE,
Laga R,
Kelsoe G ,
Saunders KO,
Fera D,
Kwong PD,
Seder RA,
Bartesaghi A,
Shaw GM,
Acharya P ,
Haynes BF
(2021) Cell , 184 , 2955 - 2972.e25