EMD-23390

Single-particle
3.0 Å
EMD-23390
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Deposition: 28/01/2021
Map released: 03/03/2021
Last modified: 12/05/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-23390
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7ljc summary report (pdf.gz) Map and 7ljc FULL report (pdf.gz)
EMICSS annotations (xml)

Allosteric modulator LY3154207 binding to SKF-81297-bound dopamine receptor 1 in complex with miniGs protein

EMD-23390

Single-particle
3.0 Å
EMD-23390
3D View Gallery
Deposition: 28/01/2021
Map released: 03/03/2021
Last modified: 12/05/2021
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Rattus norvegicus, Bos taurus, Lama glama
Sample: LY3154207 and SKF-81297-bound dopamine receptor 1 in complex with Gi protein
Fitted models: 7ljc

Deposition Authors: Zhuang Y, Krumm B, Zhang H, Zhou XE, Wang Y, Guo J, Huang X-P, Liu Y, Wang L, Cheng X, Jiang Y, Jiang H, Melcher K, Zhang C, Yi W, Roth BL, Zhang Y, Xu HE
Mechanism of dopamine binding and allosteric modulation of the human D1 dopamine receptor.
Zhuang Y , Krumm B , Zhang H, Zhou XE, Wang Y, Huang XP, Liu Y , Cheng X , Jiang Y, Jiang H , Zhang C , Yi W, Roth BL , Zhang Y , Xu HE
(2021) Cell Res , 31 , 593 - 596
PUBMED: 33750903
DOI: doi:10.1038/s41422-021-00482-0
ISSN: 1001-0602