EMD-23498
Cryo-EM structure of SARS-CoV-2 spike in complex with neutralizing antibody A23-58.1 that targets the receptor-binding domain
EMD-23498
Single-particle3.89 Å
Deposition: 17/02/2021Map released: 14/07/2021
Last modified: 25/08/2021
Sample Organism:
Severe acute respiratory syndrome coronavirus 2,
Homo sapiens
Sample: SARS-CoV-2 spike in complex with neutralizing antibody A789-58.1
Fitted models: 7lrs
Deposition Authors: Zhou T, Tsybovsky Y
Sample: SARS-CoV-2 spike in complex with neutralizing antibody A789-58.1
Fitted models: 7lrs
Deposition Authors: Zhou T, Tsybovsky Y
Ultrapotent antibodies against diverse and highly transmissible SARS-CoV-2 variants.
Wang L 
,
Zhou T ,
Zhang Y ,
Yang ES ,
Schramm CA,
Shi W,
Pegu A ,
Oloniniyi OK ,
Henry AR,
Darko S ,
Narpala SR ,
Hatcher C,
Martinez DR ,
Tsybovsky Y,
Phung E ,
Abiona OM ,
Antia A,
Cale EM ,
Chang LA ,
Choe M ,
Corbett KS ,
Davis RL,
DiPiazza AT ,
Gordon IJ ,
Hait SH ,
Hermanus T,
Kgagudi P,
Laboune F,
Leung K ,
Liu T,
Mason RD ,
Nazzari AF ,
Novik L ,
O'Connell S,
O'Dell S,
Olia AS ,
Schmidt SD ,
Stephens T,
Stringham CD ,
Talana CA ,
Teng IT,
Wagner DA ,
Widge AT ,
Zhang B ,
Roederer M ,
Ledgerwood JE,
Ruckwardt TJ ,
Gaudinski MR ,
Moore PL ,
Doria-Rose NA ,
Baric RS ,
Graham BS ,
McDermott AB ,
Douek DC,
Kwong PD ,
Mascola JR ,
Sullivan NJ ,
Misasi J
(2021) Science , 373
,
Zhou T ,
Zhang Y ,
Yang ES ,
Schramm CA,
Shi W,
Pegu A ,
Oloniniyi OK ,
Henry AR,
Darko S ,
Narpala SR ,
Hatcher C,
Martinez DR ,
Tsybovsky Y,
Phung E ,
Abiona OM ,
Antia A,
Cale EM ,
Chang LA ,
Choe M ,
Corbett KS ,
Davis RL,
DiPiazza AT ,
Gordon IJ ,
Hait SH ,
Hermanus T,
Kgagudi P,
Laboune F,
Leung K ,
Liu T,
Mason RD ,
Nazzari AF ,
Novik L ,
O'Connell S,
O'Dell S,
Olia AS ,
Schmidt SD ,
Stephens T,
Stringham CD ,
Talana CA ,
Teng IT,
Wagner DA ,
Widge AT ,
Zhang B ,
Roederer M ,
Ledgerwood JE,
Ruckwardt TJ ,
Gaudinski MR ,
Moore PL ,
Doria-Rose NA ,
Baric RS ,
Graham BS ,
McDermott AB ,
Douek DC,
Kwong PD ,
Mascola JR ,
Sullivan NJ ,
Misasi J
(2021) Science , 373