EMD-23572
Cryo-EM structure of EDC-crosslinked ConM SOSIP.v7 (ConM-EDC) in complex with bNAb PGT122
EMD-23572
Single-particle3.85 Å
Deposition: 04/03/2021Map released: 09/03/2022
Last modified: 20/09/2023
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: EDC-crosslinked ConM SOSIP.v7 in complex with PGT122 Fab
Fitted models: 7lxn
Deposition Authors: Martin GM, Ward AB
Sample: EDC-crosslinked ConM SOSIP.v7 in complex with PGT122 Fab
Fitted models: 7lxn
Deposition Authors: Martin GM, Ward AB
Profound structural conservation of chemically cross-linked HIV-1 envelope glycoprotein experimental vaccine antigens.
Martin GM,
Russell RA ,
Mundsperger P ,
Harris S ,
Jovanoska L,
Trajano LF,
Schiffner T,
Fabian K,
Tolazzi M,
Scarlatti G ,
McFarlane L,
Cheeseman H ,
Aldon Y ,
Schermer EE,
Breemen M,
Sliepen K ,
Katinger D ,
Kunert R ,
Sanders RW,
Shattock R ,
Ward AB ,
Sattentau QJ
(2023) NPJ Vaccines , 8 , 101 - 101
,
Mundsperger P ,
Harris S ,
Jovanoska L,
Trajano LF,
Schiffner T,
Fabian K,
Tolazzi M,
Scarlatti G ,
McFarlane L,
Cheeseman H ,
Aldon Y ,
Schermer EE,
Breemen M,
Sliepen K ,
Katinger D ,
Kunert R ,
Sanders RW,
Shattock R ,
Ward AB ,
Sattentau QJ
(2023) NPJ Vaccines , 8 , 101 - 101