EMD-25143

Single-particle
2.7 Å
EMD-25143
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Deposition: 14/10/2021
Map released: 19/01/2022
Last modified: 19/01/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-25143
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7sil summary report (pdf.gz) Map and 7sil FULL report (pdf.gz)
EMICSS annotations (xml)

Structure of positive allosteric modulator-bound active human calcium-sensing receptor

EMD-25143

Single-particle
2.7 Å
EMD-25143
3D View Gallery
Deposition: 14/10/2021
Map released: 19/01/2022
Last modified: 19/01/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: Homodimer human calcium sensing receptor
Fitted models: 7sil

Deposition Authors: Park J , Zuo H, Frangaj A, Fu Z , Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, Dandey VP, Tan YZ , Eng E , Lee Y, Kloss B, Liu Z, Hendrickson WA, Potter CS, Carragher B , Graziano J, Conigrave AD, Frank J , Clarke OB , Fan QR
Symmetric activation and modulation of the human calcium-sensing receptor.
Park J , Zuo H, Frangaj A, Fu Z , Yen LY, Zhang Z, Mosyak L, Slavkovich VN, Liu J, Ray KM, Cao B, Vallese F, Geng Y, Chen S, Grassucci R, Dandey VP, Tan YZ , Eng E , Lee Y, Kloss B, Liu Z, Hendrickson WA, Potter CS, Carragher B , Graziano J, Conigrave AD, Frank J , Clarke OB , Fan QR
(2021) PNAS , 118
PUBMED: 34916296
DOI: doi:10.1073/pnas.2115849118
ISSN: 1091-6490
ASTM: PNASA6