EMD-30019

Single-particle
3.2 Å
EMD-30019
3D View Gallery
Deposition: 16/02/2020
Map released: 23/12/2020
Last modified: 27/03/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-30019
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3D volume (map.gz) Experimental metadata (xml) Experimental Metadata (cif.gz)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 6lyy summary report (pdf.gz) Map and 6lyy FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of the human MCT1/Basigin-2 complex in the presence of anti-cancer drug candidate AZD3965 in the outward-open conformation.

EMD-30019

Single-particle
3.2 Å
EMD-30019
3D View Gallery
Deposition: 16/02/2020
Map released: 23/12/2020
Last modified: 27/03/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: MCT1/Basigin-2 complex
Fitted models: 6lyy

Deposition Authors: Wang N , Jiang X
Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.
Wang N , Jiang X , Zhang S, Zhu A , Yuan Y , Xu H , Lei J, Yan C
(2021) Cell , 184 , 370
PUBMED: 33333023
DOI: doi:10.1016/j.cell.2020.11.043
ISSN: 1097-4172