EMD-32372

Single-particle
3.0 Å
EMD-32372
3D View Gallery
Deposition: 10/12/2021
Map released: 25/05/2022
Last modified: 25/05/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-32372
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3D volume (map.gz) Experimental metadata (xml)
Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 7w9t summary report (pdf.gz) Map and 7w9t FULL report (pdf.gz)
EMICSS annotations (xml)

Cryo-EM structure of human Nav1.7(E406K) in complex with auxiliary beta subunits, huwentoxin-IV and saxitoxin (S6IV alpha helix conformer)

EMD-32372

Single-particle
3.0 Å
EMD-32372
3D View Gallery
Deposition: 10/12/2021
Map released: 25/05/2022
Last modified: 25/05/2022
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens
Sample: human Nav1.7 in complex with beta1, beta2 and Huwentoxin
Fitted models: 7w9t

Deposition Authors: Yan N, Huang G, Liu D, Wei P
High-resolution structures of human Na v 1.7 reveal gating modulation through alpha-pi helical transition of S6 IV.
Huang G, Liu D, Wang W, Wu Q, Chen J, Pan X , Shen H, Yan N
(2022) Cell Rep , 39 , 110735 - 110735
PUBMED: 35476982
DOI: doi:10.1016/j.celrep.2022.110735
ISSN: 2211-1247