EMD-33651
SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7 (focused refinement on Fab-RBD interface)
EMD-33651
Single-particle4.03 Å
Deposition: 21/06/2022
Map released: 02/08/2023
Last modified: 30/10/2024
Sample Organism:
Homo sapiens
Sample: SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7
Fitted models: 7y72
Deposition Authors: Chia WN , Tan CW , Tan AWK , Young B , Starr TN , Lopez E , Fibriansah G , Barr J , Cheng S , Yeoh AYY, Yap WC , Lim BL, Ng TS , Sia WR , Zhu F , Chen S , Zhang J , Greaney AJ , Chen M , Au GG , Paradkar P, Peiris M , Chung AW , Bloom JD , Lye D , Lok SM, Wang LF
Sample: SARS-CoV-2 spike glycoprotein trimer complexed with Fab fragment of anti-RBD antibody E7
Fitted models: 7y72
Deposition Authors: Chia WN , Tan CW , Tan AWK , Young B , Starr TN , Lopez E , Fibriansah G , Barr J , Cheng S , Yeoh AYY, Yap WC , Lim BL, Ng TS , Sia WR , Zhu F , Chen S , Zhang J , Greaney AJ , Chen M , Au GG , Paradkar P, Peiris M , Chung AW , Bloom JD , Lye D , Lok SM, Wang LF
Potent pan huACE2-dependent sarbecovirus neutralizing monoclonal antibodies isolated from a BNT162b2-vaccinated SARS survivor.
Chia WN ,
Tan CW ,
Tan AWK ,
Young B ,
Starr TN ,
Lopez E ,
Fibriansah G ,
Barr J ,
Cheng S ,
Yeoh AY,
Yap WC ,
Lim BL,
Ng TS ,
Sia WR ,
Zhu F ,
Chen S ,
Zhang J ,
Kwek MSS ,
Greaney AJ ,
Chen M ,
Au GG ,
Paradkar PN ,
Peiris M ,
Chung AW ,
Bloom JD ,
Lye D ,
Lok S ,
Wang LF
(2023) Sci Adv , 9 , eade3470 - eade3470
(2023) Sci Adv , 9 , eade3470 - eade3470