EMD-37210

Single-particle
3.17 Å
EMD-37210
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Deposition: 17/08/2023
Map released: 19/06/2024
Last modified: 19/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links

EMD-37210
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Map-only Validation report (pdf.gz) Map-only Validation report (cif.gz) Map-only Validation report (xml.gz)
Map and PDB model 8kg5 summary report (pdf.gz) Map and 8kg5 FULL report (pdf.gz)
EMICSS annotations (xml)

Prefusion RSV F Bound to Lonafarnib and D25 Fab

EMD-37210

Single-particle
3.17 Å
EMD-37210
3D View Gallery
Deposition: 17/08/2023
Map released: 19/06/2024
Last modified: 19/06/2024
Overview 3D View Sample Experiment Validation Volume Browser Additional data Links
Sample Organism: Homo sapiens, Human respiratory syncytial virus A (strain A2), Enterobacteria phage T4
Sample: Prefusion RSV F Bound to Lonafarnib and D25 Fab
Fitted models: 8kg5

Deposition Authors: Yang Q, Xue B, Liu F , Peng W, Chen X
Farnesyltransferase inhibitor lonafarnib suppresses respiratory syncytial virus infection by blocking conformational change of fusion glycoprotein.
Yang Q, Xue B, Liu F , Lu Y, Tang J, Yan M, Wu Q, Chen R, Zhou A, Liu L, Liu J, Qu C, Wu Q, Fu M, Zhong J, Dong J, Chen S, Wang F, Zhou Y, Zheng J, Peng W, Shang J , Chen X
(2024) Signal Transduct Target Ther , 9 , 144 - 144
PUBMED: 38853183
DOI: doi:10.1038/s41392-024-01858-5
ISSN: 2059-3635