EMD-46533
Cryo-EM structure of CCR6 bound by SQA1 and OXM2
EMD-46533
Single-particle3.02 Å
Deposition: 09/08/2024Map released: 11/09/2024
Last modified: 11/09/2024
Sample Organism:
Homo sapiens,
synthetic construct
Sample: CCR6-BRIL/Fab/Nb in complex with SQA1 and OXM2
Fitted models: 9d3e
Deposition Authors: Wasilko DJ, Wu H
Sample: CCR6-BRIL/Fab/Nb in complex with SQA1 and OXM2
Fitted models: 9d3e
Deposition Authors: Wasilko DJ, Wu H
Structural basis for CCR6 modulation by allosteric antagonists.
Wasilko DJ,
Gerstenberger BS ,
Farley KA ,
Li W,
Alley J,
Schnute ME ,
Unwalla RJ,
Victorino J,
Crouse KK,
Ding R,
Sahasrabudhe PV ,
Vincent F ,
Frisbie RK,
Dermenci A,
Flick A ,
Choi C ,
Chinigo G,
Mousseau JJ,
Trujillo JI,
Nuhant P,
Mondal P,
Lombardo V,
Lamb D,
Hogan BJ ,
Minhas GS,
Segala E,
Oswald C,
Windsor IW ,
Han S ,
Rappas M,
Cooke RM,
Calabrese MF ,
Berstein G,
Thorarensen A,
Wu H
(2024) Nat Commun , 15 , 7574 - 7574
,
Farley KA ,
Li W,
Alley J,
Schnute ME ,
Unwalla RJ,
Victorino J,
Crouse KK,
Ding R,
Sahasrabudhe PV ,
Vincent F ,
Frisbie RK,
Dermenci A,
Flick A ,
Choi C ,
Chinigo G,
Mousseau JJ,
Trujillo JI,
Nuhant P,
Mondal P,
Lombardo V,
Lamb D,
Hogan BJ ,
Minhas GS,
Segala E,
Oswald C,
Windsor IW ,
Han S ,
Rappas M,
Cooke RM,
Calabrese MF ,
Berstein G,
Thorarensen A,
Wu H
(2024) Nat Commun , 15 , 7574 - 7574