EMD-8078
BG505 SOSIP.664 HIV-1 Env trimer in complex with anti-HIV CH235.12 wk323 Fab
EMD-8078
Single-particle17.0 Å
Deposition: 20/02/2016Map released: 23/03/2016
Last modified: 14/02/2018
Sample Organism:
Human immunodeficiency virus 1,
Homo sapiens
Sample: Complex containing 3 copies of CH235.12 wk323 anti-HIV Fab bound to a trimer of HIV-1 Env BG505 SOSIP.664
Deposition Authors: Ozorowski G, Ward AB
Sample: Complex containing 3 copies of CH235.12 wk323 anti-HIV Fab bound to a trimer of HIV-1 Env BG505 SOSIP.664
Deposition Authors: Ozorowski G, Ward AB
Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimic Antibody.
Bonsignori M 
,
Zhou T ,
Sheng Z,
Chen L,
Gao F,
Joyce MG,
Ozorowski G,
Chuang GY,
Schramm CA,
Wiehe K,
Alam SM,
Bradley T,
Gladden MA,
Hwang KK,
Iyengar S,
Kumar A,
Lu X,
Luo K,
Mangiapani MC,
Parks RJ,
Song H,
Acharya P ,
Bailer RT,
Cao A,
Druz A,
Georgiev IS,
Kwon YD,
Louder MK,
Zhang B,
Zheng A,
Hill BJ ,
Kong R,
Soto C,
Mullikin JC,
Douek DC,
Montefiori DC,
Moody MA,
Shaw GM,
Hahn BH,
Kelsoe G ,
Hraber PT ,
Korber BT ,
Boyd SD ,
Fire AZ,
Kepler TB ,
Shapiro L,
Ward AB,
Mascola JR,
Liao HX,
Kwong PD,
Haynes BF
(2016) Cell , 165 , 449 - 463
,
Zhou T ,
Sheng Z,
Chen L,
Gao F,
Joyce MG,
Ozorowski G,
Chuang GY,
Schramm CA,
Wiehe K,
Alam SM,
Bradley T,
Gladden MA,
Hwang KK,
Iyengar S,
Kumar A,
Lu X,
Luo K,
Mangiapani MC,
Parks RJ,
Song H,
Acharya P ,
Bailer RT,
Cao A,
Druz A,
Georgiev IS,
Kwon YD,
Louder MK,
Zhang B,
Zheng A,
Hill BJ ,
Kong R,
Soto C,
Mullikin JC,
Douek DC,
Montefiori DC,
Moody MA,
Shaw GM,
Hahn BH,
Kelsoe G ,
Hraber PT ,
Korber BT ,
Boyd SD ,
Fire AZ,
Kepler TB ,
Shapiro L,
Ward AB,
Mascola JR,
Liao HX,
Kwong PD,
Haynes BF
(2016) Cell , 165 , 449 - 463