EMD-9320
Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody DFPH-a.15 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
EMD-9320
Single-particle4.2 Å
Deposition: 12/11/2018Map released: 24/07/2019
Last modified: 29/07/2020
Sample Organism:
Homo sapiens,
Human immunodeficiency virus 1,
Macaca mulatta
Sample: Quaternary complex of HIV-1 Env BG505 DS-SOSIP with antibodies DFPH-a.15, VRC03 and PGT122.
Fitted models: 6n1w
Deposition Authors: Acharya P, Kwong PD
Sample: Quaternary complex of HIV-1 Env BG505 DS-SOSIP with antibodies DFPH-a.15, VRC03 and PGT122.
Fitted models: 6n1w
Deposition Authors: Acharya P, Kwong PD
Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Kong R,
Duan H 
,
Sheng Z,
Xu K,
Acharya P ,
Chen X,
Cheng C,
Dingens AS,
Gorman J,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Chuang GY,
Chao CW,
Gu Y,
Jafari AJ,
Louder MK,
O'Dell S,
Rowshan AP,
Viox EG,
Wang Y,
Choi CW,
Corcoran MM ,
Corrigan AR ,
Dandey VP,
Eng ET ,
Geng H,
Foulds KE,
Guo Y ,
Kwon YD,
Lin B,
Liu K,
Mason RD,
Nason MC,
Ohr TY,
Ou L,
Rawi R,
Sarfo EK ,
Schon A,
Todd JP,
Wang S,
Wei H,
Wu W,
Mullikin JC,
Bailer RT,
Doria-Rose NA,
Karlsson Hedestam GB,
Scorpio DG,
Overbaugh J,
Bloom JD,
Carragher B,
Potter CS,
Shapiro L,
Kwong PD,
Mascola JR
(2019) Cell , 178 , 567 - 584.e19
,
Sheng Z,
Xu K,
Acharya P ,
Chen X,
Cheng C,
Dingens AS,
Gorman J,
Sastry M,
Shen CH,
Zhang B,
Zhou T,
Chuang GY,
Chao CW,
Gu Y,
Jafari AJ,
Louder MK,
O'Dell S,
Rowshan AP,
Viox EG,
Wang Y,
Choi CW,
Corcoran MM ,
Corrigan AR ,
Dandey VP,
Eng ET ,
Geng H,
Foulds KE,
Guo Y ,
Kwon YD,
Lin B,
Liu K,
Mason RD,
Nason MC,
Ohr TY,
Ou L,
Rawi R,
Sarfo EK ,
Schon A,
Todd JP,
Wang S,
Wei H,
Wu W,
Mullikin JC,
Bailer RT,
Doria-Rose NA,
Karlsson Hedestam GB,
Scorpio DG,
Overbaugh J,
Bloom JD,
Carragher B,
Potter CS,
Shapiro L,
Kwong PD,
Mascola JR
(2019) Cell , 178 , 567 - 584.e19