› › Structure analysis

STRUCTURE OF A DNA:RNA HYBRID DUPLEX: WHY RNASE H DOES NOT CLEAVE PURE RNA

Solution NMR
PDB entry 124d coloured by chain, front view.
PDB entry 124d coloured by chain, side view.
PDB entry 124d coloured by chain, top view.
Source organism: Synthetic construct
Assembly composition:
hetero dimer (preferred)
Entry contents: 1 distinct DNA molecule
1 distinct RNA molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero dimer
Accessible surface area: 3180.58 Å2
Buried surface area: 756.35 Å2
Dissociation area: 378.17 Å2
Dissociation energy (ΔGdiss): -6.22 kcal/mol
Dissociation entropy (TΔSdiss): 7.98 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-113315

Macromolecules

DNA chain A
Name: DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*G)-3')
Representative chains: A
Source organism: Synthetic construct [32630]
Expression system: Not provided
Length: 8 nucleotides
Theoretical weight: 2.43 KDa
DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*G)-3') in PDB entry 124d, assembly 1, front view.
DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*G)-3') in PDB entry 124d, assembly 1, side view.
DNA (5'-D(*GP*TP*CP*AP*CP*AP*TP*G)-3') in PDB entry 124d, assembly 1, top view.
Molecule details ›

Search similar DNA

RNA chain B
Name: RNA (5'-R(*CP*AP*UP*GP*UP*GP*AP*C)-3')
Representative chains: B
Source organism: Synthetic construct [32630]
Expression system: Not provided
Length: 8 nucleotides
Theoretical weight: 2.53 KDa
RNA (5'-R(*CP*AP*UP*GP*UP*GP*AP*C)-3') in PDB entry 124d, assembly 1, front view.
RNA (5'-R(*CP*AP*UP*GP*UP*GP*AP*C)-3') in PDB entry 124d, assembly 1, side view.
RNA (5'-R(*CP*AP*UP*GP*UP*GP*AP*C)-3') in PDB entry 124d, assembly 1, top view.
Molecule details ›

Search similar RNA

Quick links