› 1vyg

X-ray diffraction
2.4Å resolution

schistosoma mansoni fatty acid binding protein in complex with arachidonic acid

Released:
DOI: 10.2210/pdb1vyg/pdb
PDB entry 1vyg coloured by chain, front view.
PDB entry 1vyg coloured by chain, side view.
PDB entry 1vyg coloured by chain, top view.
Source organism: Schistosoma mansoni
Primary publication:
Schistosoma mansoni fatty acid binding protein: specificity and functional control as revealed by crystallographic structure.
Angelucci F, Johnson KA, Baiocco P, Miele AE, Brunori M, Valle C, Vigorosi F, Troiani AR, Liberti P, Cioli D, Klinkert MQ, Bellelli A
Biochemistry 43 13000-11 (2004)
PMID: 15476393

Function and Biology Details

Biochemical function:
Biological process:
  • not assigned
Cellular component:
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-151526 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
14 kDa fatty acid-binding protein Chain: A
Molecule details ›
Chain: A
Length: 135 amino acids
Theoretical weight: 15.01 KDa
Source organism: Schistosoma mansoni
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P29498 (Residues: 1-133; Coverage: 100%)
Sequence domains: Lipocalin / cytosolic fatty-acid binding protein family
Structure domains: Lipocalin

Ligands and Environments

1 bound ligand:
Ligand ACD 1 x ACD
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: ELETTRA BEAMLINE 5.2R
Spacegroup: P21212
Unit cell:
a: 42.29Å b: 91.01Å c: 35.33Å
α: 90° β: 90° γ: 90°
R-values:
R R work R free
0.217 0.213 0.283
Expression system: Escherichia coli BL21(DE3)

Quick links

Citations

2 review citations

Current Status of the Sm14/GLA-SE Schistosomiasis Vaccine: Overcoming Barriers and Paradigms towards the First Anti-Parasitic Human(itarian) Vaccine.
Tendler et al. (2018)
1 more

4 mentions without citation

The Recognition of Identical Ligands by Unrelated Proteins.
Barelier et al. (2015)
3 more