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RECOGNITION BY MAX OF ITS COGNATE DNA THROUGH A DIMERIC B/HLH/Z DOMAIN

X-ray diffraction
2.9Å resolution
PDB entry 1an2 coloured by chain, front view.
PDB entry 1an2 coloured by chain, side view.
PDB entry 1an2 coloured by chain, top view.
Source organisms:
Assembly composition:
hetero tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule
1 distinct DNA molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Protein max and DNA
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Multimeric state: hetero tetramer
Accessible surface area: 19084.48 Å2
Buried surface area: 7296.2 Å2
Dissociation area: 2,655.12 Å2
Dissociation energy (ΔGdiss): 34.19 kcal/mol
Dissociation entropy (TΔSdiss): 24.04 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-113429

Macromolecules

Protein max
Chain: A
Length: 86 amino acids
Theoretical weight: 10.22 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P61244 (Residues: 22-107; Coverage: 54%)
Gene names: BHLHD4, MAX
Pfam: Helix-loop-helix DNA-binding domain
InterPro:
CATH: Helix-loop-helix DNA-binding domain
SCOP: HLH, helix-loop-helix DNA-binding domain
Protein max in PDB entry 1an2, assembly 1, front view.
Protein max in PDB entry 1an2, assembly 1, side view.
Protein max in PDB entry 1an2, assembly 1, top view.
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DNA chain B
Name: DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3')
Representative chains: B
Source organism: Mus musculus [10090]
Expression system: Escherichia coli [562]
Length: 22 nucleotides
Theoretical weight: 6.75 KDa
DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3') in PDB entry 1an2, assembly 1, front view.
DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3') in PDB entry 1an2, assembly 1, side view.
DNA (5'-D(*GP*TP*GP*TP*AP*GP*GP*TP*CP*AP*CP*GP*TP*GP*AP*CP*C P*TP*AP*CP*AP*C)- 3') in PDB entry 1an2, assembly 1, top view.
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