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CRYSTAL STRUCTURE OF CANINE AND BOVINE GRANULOCYTE-COLONY STIMULATING FACTOR (G-CSF)

X-ray diffraction
2.3Å resolution
PDB entry 1bgd coloured by chain, front view.
PDB entry 1bgd coloured by chain, side view.
PDB entry 1bgd coloured by chain, top view.
Source organism: Canis lupus familiaris
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Granulocyte colony-stimulating factor
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Multimeric state: monomeric
Accessible surface area: 7741.13 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-153041

Macromolecules

Granulocyte colony-stimulating factor
Chain: A
Length: 175 amino acids
Theoretical weight: 18.87 KDa
Source organism: Canis lupus familiaris
Expression system: Not provided
UniProt:
  • Canonical: P35834 (Residues: 1-175; Coverage: 100%)
Gene name: CSF3
Pfam: Granulocyte colony-stimulating factor
InterPro:
CATH: Growth Hormone; Chain: A;
SCOP: Long-chain cytokines
Granulocyte colony-stimulating factor in PDB entry 1bgd, assembly 1, front view.
Granulocyte colony-stimulating factor in PDB entry 1bgd, assembly 1, side view.
Granulocyte colony-stimulating factor in PDB entry 1bgd, assembly 1, top view.
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