Function and Biology Details
Reaction catalysed:
Preferential cleavage: Arg-|-, Lys-|-.
Biochemical function:
Biological process:
Cellular component:
Sequence domains:
Structure domains:
Structure analysis Details
Assembly composition:
hetero dimer (preferred)
Assembly name:
Bdellastasin and Serine protease 1 (preferred)
PDBe Complex ID:
PDB-CPX-133336 (preferred)
Entry contents:
2 distinct polypeptide molecules
Macromolecules (2 distinct):
Serine protease 1
Molecule details ›
Chains: A, B, C, D, E, F
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Length: 223 amino acids
Theoretical weight: 23.32 KDa
Source organism: Bos taurus
UniProt:
- Canonical:
P00760 (Residues: 24-246; Coverage: 97%)
Sequence domains: Trypsin
Structure domains: Trypsin-like serine proteases
Bdellastasin
Molecule details ›
Chains: G, H, I, J, K, L
Length: 59 amino acids
Theoretical weight: 6.35 KDa
Source organism: Hirudo medicinalis
Expression system: Saccharomyces cerevisiae
UniProt:
Structure domains: Antistasin; domain 1
Length: 59 amino acids
Theoretical weight: 6.35 KDa
Source organism: Hirudo medicinalis
Expression system: Saccharomyces cerevisiae
UniProt:
- Canonical: P82107 (Residues: 1-59; Coverage: 100%)
Structure domains: Antistasin; domain 1
Ligands and Environments
No bound ligands
No modified residues
Experiments and Validation Details
X-ray source:
RIGAKU RU200
Spacegroup:
P21
Expression system: Saccharomyces cerevisiae
