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ANTI-P24 (HIV-1) FAB FRAGMENT CB41

X-ray diffraction
2.8Å resolution
PDB entry 1cfq coloured by chain, front view.
PDB entry 1cfq coloured by chain, side view.
PDB entry 1cfq coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-light kappa chain and IG-heavy chain
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Multimeric state: hetero dimer
Accessible surface area: 19786.11 Å2
Buried surface area: 3330.31 Å2
Dissociation area: 1,665.16 Å2
Dissociation energy (ΔGdiss): 17.73 kcal/mol
Dissociation entropy (TΔSdiss): 13.13 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-134660

Macromolecules

Immunoglobulin kappa constant
Chain: A
Length: 214 amino acids
Theoretical weight: 23.93 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Immunoglobulin kappa constant in PDB entry 1cfq, assembly 1, front view.
Immunoglobulin kappa constant in PDB entry 1cfq, assembly 1, side view.
Immunoglobulin kappa constant in PDB entry 1cfq, assembly 1, top view.
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Ig gamma-2A chain C region secreted form
Chain: B
Length: 213 amino acids
Theoretical weight: 22.67 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01864 (Residues: 1-101; Coverage: 30%)
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Ig gamma-2A chain C region secreted form in PDB entry 1cfq, assembly 1, front view.
Ig gamma-2A chain C region secreted form in PDB entry 1cfq, assembly 1, side view.
Ig gamma-2A chain C region secreted form in PDB entry 1cfq, assembly 1, top view.
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