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ANTI-P24 (HIV-1) FAB FRAGMENT CB41 COMPLEXED WITH AN EPITOPE-UNRELATED D-PEPTIDE

X-ray diffraction
2.8Å resolution
PDB entry 1cft coloured by chain, front view.
PDB entry 1cft coloured by chain, side view.
PDB entry 1cft coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero trimer (preferred)
Entry contents: 3 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero trimer
Accessible surface area: 19654.42 Å2
Buried surface area: 4311.2 Å2
Dissociation area: 437.03 Å2
Dissociation energy (ΔGdiss): 1.45 kcal/mol
Dissociation entropy (TΔSdiss): 5.52 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-134663

Macromolecules

Immunoglobulin kappa constant
Chain: A
Length: 214 amino acids
Theoretical weight: 23.93 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-107; Coverage: 100%)
Gene name: Igkc
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Immunoglobulin kappa constant in PDB entry 1cft, assembly 1, front view.
Immunoglobulin kappa constant in PDB entry 1cft, assembly 1, side view.
Immunoglobulin kappa constant in PDB entry 1cft, assembly 1, top view.
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Ig gamma-2A chain C region secreted form
Chain: B
Length: 213 amino acids
Theoretical weight: 22.67 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01864 (Residues: 1-101; Coverage: 30%)
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Ig gamma-2A chain C region secreted form in PDB entry 1cft, assembly 1, front view.
Ig gamma-2A chain C region secreted form in PDB entry 1cft, assembly 1, side view.
Ig gamma-2A chain C region secreted form in PDB entry 1cft, assembly 1, top view.
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PROTEIN (ANTIGEN BOUND PEPTIDE)
Chain: C
Length: 5 amino acids
Theoretical weight: 528 Da
PROTEIN (ANTIGEN BOUND PEPTIDE) in PDB entry 1cft, assembly 1, front view.
PROTEIN (ANTIGEN BOUND PEPTIDE) in PDB entry 1cft, assembly 1, side view.
PROTEIN (ANTIGEN BOUND PEPTIDE) in PDB entry 1cft, assembly 1, top view.
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