Function and Biology

CRYSTAL STRUCTURE OF FERREDOXIN THIOREDOXIN REDUCTASE

Source organism: Synechocystis sp. PCC 6803
Biochemical function: oxidoreductase activity
Biological process: photosynthesis
Cellular component: not assigned

EC 1.8.7.2: Ferredoxin:thioredoxin reductase

Reaction catalysed:
2 reduced ferredoxin + thioredoxin disulfide = 2 oxidized ferredoxin + thioredoxin + 2 H(+)
Systematic name:
Ferredoxin:thioredoxin disulfide oxidoreductase

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF02941
Domain description: Ferredoxin thioredoxin reductase variable alpha chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
The deposited structure of PDB entry 1dj7 contains 1 copy of Pfam domain PF02941 (Ferredoxin thioredoxin reductase variable alpha chain) in Ferredoxin-thioredoxin reductase, variable chain. Showing 1 copy in chain B.

PF02943
Domain description: Ferredoxin thioredoxin reductase catalytic beta chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
The deposited structure of PDB entry 1dj7 contains 1 copy of Pfam domain PF02943 (Ferredoxin thioredoxin reductase catalytic beta chain) in Ferredoxin-thioredoxin reductase, catalytic chain. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR004209
Domain description: Ferredoxin thioredoxin reductase catalytic beta subunit
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
IPR036644
Domain description: Ferredoxin thioredoxin reductase catalytic beta subunit superfamily
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
IPR004207
Domain description: Ferredoxin thioredoxin reductase, alpha chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
IPR044166
Domain description: Ferredoxin-thioredoxin reductase, variable chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
IPR008990
Domain description: Electron transport accessory-like domain superfamily
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
IPR024707
Domain description: Ferredoxin-thioredoxin reductase catalytic subunit, cyanobacteria-type
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain

Structure domains

CATH CATH domains
2.30.30.50
Class: Mainly Beta
Architecture: Roll
Topology: SH3 type barrels.
Homology: SH3 type barrels.
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
The deposited structure of PDB entry 1dj7 contains 1 copy of CATH domain 2.30.30.50 (SH3 type barrels.) in Ferredoxin-thioredoxin reductase, variable chain. Showing 1 copy in chain B.
3.90.460.10
Class: Alpha Beta
Architecture: Alpha-Beta Complex
Topology: Ferredoxin Thioredoxin Reductase
Homology: Ferredoxin thioredoxin reductase catalytic beta subunit
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
The deposited structure of PDB entry 1dj7 contains 1 copy of CATH domain 3.90.460.10 (Ferredoxin Thioredoxin Reductase) in Ferredoxin-thioredoxin reductase, catalytic chain. Showing 1 copy in chain A.
SCOP SCOP annotations
50098
Class: All beta proteins
Fold: SH3-like barrel
Superfamily: Electron transport accessory proteins
Occurring in:
  1. Ferredoxin-thioredoxin reductase, variable chain
The deposited structure of PDB entry 1dj7 contains 1 copy of SCOP domain 50098 (Ferredoxin thioredoxin reductase (FTR), alpha (variable) chain) in Ferredoxin-thioredoxin reductase, variable chain. Showing 1 copy in chain B.
57663
Class: Small proteins
Fold: Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
Superfamily: Ferredoxin thioredoxin reductase (FTR), catalytic beta chain
Occurring in:
  1. Ferredoxin-thioredoxin reductase, catalytic chain
The deposited structure of PDB entry 1dj7 contains 1 copy of SCOP domain 57663 (Ferredoxin thioredoxin reductase (FTR), catalytic beta chain) in Ferredoxin-thioredoxin reductase, catalytic chain. Showing 1 copy in chain A.