› › Structure analysis

CRYSTAL STRUCTURE OF HUMAN TRANSTHYRETIN IN COMPLEX WITH O-TRIFLUOROMETHYLPHENYL ANTHRANILIC ACID

X-ray diffraction
1.9Å resolution
PDB entry 1dvz coloured by chain, front view.
PDB entry 1dvz coloured by chain, side view.
PDB entry 1dvz coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Transthyretin
hide full assembly name
Multimeric state: homo tetramer
Accessible surface area: 18327.35 Å2
Buried surface area: 7433.31 Å2
Dissociation area: 1,749.4 Å2
Dissociation energy (ΔGdiss): 4.22 kcal/mol
Dissociation entropy (TΔSdiss): 12.79 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-136168

Macromolecules

Transthyretin
Chains: A, B
Length: 124 amino acids
Theoretical weight: 13.42 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: P02766 (Residues: 21-144; Coverage: 98%)
Gene names: PALB, TTR
Pfam: HIUase/Transthyretin family
InterPro:
CATH: Transthyretin/hydroxyisourate hydrolase domain
SCOP: Transthyretin (synonym: prealbumin)
Transthyretin in PDB entry 1dvz, assembly 1, front view.
Transthyretin in PDB entry 1dvz, assembly 1, side view.
Transthyretin in PDB entry 1dvz, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links