Structure analysis

CRYSTAL STRUCTURE OF THE LAC REPRESSOR DIMER BOUND TO OPERATOR AND THE ANTI-INDUCER ONPF

X-ray diffraction
2.6Å resolution
Source organism: Escherichia coli
Assemblies composition:
hetero tetramer (preferred)
monomeric
Entry contents: 1 distinct polypeptide molecule
1 distinct DNA molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero tetramer
Accessible surface area: 29279.29 Å2
Buried surface area: 11200.76 Å2
Dissociation area: 2,015.32 Å2
Dissociation energy (ΔGdiss): 24.07 kcal/mol
Dissociation entropy (TΔSdiss): 12.03 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-113732
Assembly 2
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Multimeric state: monomeric
Accessible surface area: 13106.09 Å2
Buried surface area: 648.98 Å2
Dissociation area: 324.49 Å2
Dissociation energy (ΔGdiss): -4.48 kcal/mol
Dissociation entropy (TΔSdiss): 3.89 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-136464

Macromolecules

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Name: DNA (5'-D(*GP*AP*AP*T*TP*GP*TP*GP*AP*GP*CP*GP*CP*TP*CP*AP*CP*AP*AP*TP*T)-3')
Representative chains: D, E
Source organism: Escherichia coli [562]
Expression system: Not provided
Length: 21 nucleotides
Theoretical weight: 6.46 KDa

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