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GDP-FUCOSE SYNTHETASE FROM E. COLI

X-ray diffraction
2.2Å resolution
PDB entry 1gfs coloured by chain, front view.
PDB entry 1gfs coloured by chain, side view.
PDB entry 1gfs coloured by chain, top view.
Source organism: Escherichia coli K-12
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: GDP-L-fucose synthase
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Multimeric state: homo dimer
Accessible surface area: 25654.24 Å2
Buried surface area: 3016.48 Å2
Dissociation area: 1,508.24 Å2
Dissociation energy (ΔGdiss): 14.58 kcal/mol
Dissociation entropy (TΔSdiss): 13.74 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-152194

Macromolecules

GDP-L-fucose synthase
Chain: A
Length: 321 amino acids
Theoretical weight: 36.19 KDa
Source organism: Escherichia coli K-12
Expression system: Escherichia coli BL21
UniProt:
  • Canonical: P32055 (Residues: 1-321; Coverage: 100%)
Gene names: JW2037, b2052, fcl, wcaG, yefB
Pfam: NAD dependent epimerase/dehydratase family
InterPro:
CATH:
SCOP: Tyrosine-dependent oxidoreductases
GDP-L-fucose synthase in PDB entry 1gfs, assembly 1, front view.
GDP-L-fucose synthase in PDB entry 1gfs, assembly 1, side view.
GDP-L-fucose synthase in PDB entry 1gfs, assembly 1, top view.
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