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Crystal Structure of Laccase from Melanocarpus albomyces in Four Copper Form

Source organism: Melanocarpus albomyces
Biochemical function: hydroquinone:oxygen oxidoreductase activity
Biological process: lignin catabolic process
Cellular component: extraorganismal space

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EC 1.10.3.2: Laccase

Reaction catalysed:
4 benzenediol + O(2) = 4 benzosemiquinone + 2 H(2)O
Systematic name:
Benzenediol:oxygen oxidoreductase
Alternative Name(s):
  • Urishiol oxidase
  • Urushiol oxidase
  • p-diphenol oxidase

GO terms

Sequence families

Pfam Protein families (Pfam)
PF07731
Domain description: Multicopper oxidase
Occurring in:
  1. Laccase-1
The deposited structure of PDB entry 1gw0 contains 2 copies of Pfam domain PF07731 (Multicopper oxidase) in Laccase-1. Showing 1 copy in chain A.

PF00394
Domain description: Multicopper oxidase
Occurring in:
  1. Laccase-1
The deposited structure of PDB entry 1gw0 contains 2 copies of Pfam domain PF00394 (Multicopper oxidase) in Laccase-1. Showing 1 copy in chain A.

PF07732
Domain description: Multicopper oxidase
Occurring in:
  1. Laccase-1
The deposited structure of PDB entry 1gw0 contains 2 copies of Pfam domain PF07732 (Multicopper oxidase) in Laccase-1. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR008972
Domain description: Cupredoxin
Occurring in:
  1. Laccase-1
IPR002355
Domain description: Multicopper oxidase, copper-binding site
Occurring in:
  1. Laccase-1
IPR033138
Domain description: Multicopper oxidases, conserved site
Occurring in:
  1. Laccase-1
IPR011706
Domain description: Multicopper oxidase, C-terminal
Occurring in:
  1. Laccase-1
IPR001117
Domain description: Multicopper oxidase, second cupredoxin domain
Occurring in:
  1. Laccase-1
IPR045087
Domain description: Multicopper oxidase
Occurring in:
  1. Laccase-1
IPR011707
Domain description: Multicopper oxidase-like, N-terminal
Occurring in:
  1. Laccase-1

Structure domain

CATH CATH domain
2.60.40.420
Class: Mainly Beta
Architecture: Sandwich
Topology: Immunoglobulin-like
Homology: Cupredoxins - blue copper proteins
Occurring in:
  1. Laccase-1
The deposited structure of PDB entry 1gw0 contains 6 copies of CATH domain 2.60.40.420 (Immunoglobulin-like) in Laccase-1. Showing 3 copies in chain A.
SCOP SCOP annotation
49550
Class: All beta proteins
Fold: Cupredoxin-like
Superfamily: Cupredoxins
Occurring in:
  1. Laccase-1
The deposited structure of PDB entry 1gw0 contains 6 copies of SCOP domain 49550 (Multidomain cupredoxins) in Laccase-1. Showing 3 copies in chain A.

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