› › Structure analysis

THE CRYSTAL STRUCTURE OF AFFINITY-MATURED HUMAN GROWTH HORMONE AT 2 ANGSTROMS RESOLUTION

X-ray diffraction
2Å resolution
PDB entry 1huw coloured by chain, front view.
PDB entry 1huw coloured by chain, side view.
PDB entry 1huw coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Somatotropin
hide full assembly name
Multimeric state: homo dimer
Accessible surface area: 17510.85 Å2
Buried surface area: 1301.1 Å2
Dissociation area: 650.55 Å2
Dissociation energy (ΔGdiss): -4.39 kcal/mol
Dissociation entropy (TΔSdiss): 12.3 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-134131

Macromolecules

Somatotropin
Chain: A
Length: 191 amino acids
Theoretical weight: 21.99 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P01241 (Residues: 27-217; Coverage: 100%)
Gene name: GH1
Pfam: Somatotropin hormone family
InterPro:
CATH: Growth Hormone; Chain: A;
SCOP: Long-chain cytokines
Somatotropin in PDB entry 1huw, assembly 1, front view.
Somatotropin in PDB entry 1huw, assembly 1, side view.
Somatotropin in PDB entry 1huw, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links