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Crystal Structure of P.aeruginosa Peptide deformylase Complexed with Antibiotic Actinonin

X-ray diffraction
1.85Å resolution
PDB entry 1ix1 coloured by chain, front view.
PDB entry 1ix1 coloured by chain, side view.
PDB entry 1ix1 coloured by chain, top view.
Source organism: Pseudomonas aeruginosa
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Peptide deformylase
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Multimeric state: homo dimer
Accessible surface area: 16664.75 Å2
Buried surface area: 3541.69 Å2
Dissociation area: 557.47 Å2
Dissociation energy (ΔGdiss): -15.22 kcal/mol
Dissociation entropy (TΔSdiss): 12.15 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-191503

Macromolecules

Peptide deformylase
Chains: A, B
Length: 171 amino acids
Theoretical weight: 19.81 KDa
Source organism: Pseudomonas aeruginosa
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9I7A8 (Residues: 1-168; Coverage: 100%)
Gene names: PA0019, def
Pfam: Polypeptide deformylase
InterPro:
CATH: Peptide deformylase
SCOP: Peptide deformylase
Peptide deformylase in PDB entry 1ix1, assembly 1, front view.
Peptide deformylase in PDB entry 1ix1, assembly 1, side view.
Peptide deformylase in PDB entry 1ix1, assembly 1, top view.
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