Function and Biology

Crystal structure of the FtsH ATPase domain from Thermus thermophilus

Source organism: Thermus thermophilus
Biochemical function: ATP hydrolysis activity
Biological process: not assigned
Cellular component: not assigned

GO terms

Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF17862
Domain description: AAA+ lid domain
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
The deposited structure of PDB entry 1ixz contains 1 copy of Pfam domain PF17862 (AAA+ lid domain) in ATP-dependent zinc metalloprotease FtsH. Showing 1 copy in chain A.

PF00004
Domain description: ATPase family associated with various cellular activities (AAA)
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
The deposited structure of PDB entry 1ixz contains 1 copy of Pfam domain PF00004 (ATPase family associated with various cellular activities (AAA)) in ATP-dependent zinc metalloprotease FtsH. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR027417
Domain description: P-loop containing nucleoside triphosphate hydrolase
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
IPR041569
Domain description: AAA ATPase, AAA+ lid domain
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
IPR003960
Domain description: ATPase, AAA-type, conserved site
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
IPR003959
Domain description: ATPase, AAA-type, core
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
IPR003593
Domain description: AAA+ ATPase domain
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH

Structure domains

CATH CATH domains
1.10.8.60
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helicase, Ruva Protein; domain 3
Homology: Helicase, Ruva Protein; domain 3
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
The deposited structure of PDB entry 1ixz contains 1 copy of CATH domain 1.10.8.60 (Helicase, Ruva Protein; domain 3) in ATP-dependent zinc metalloprotease FtsH. Showing 1 copy in chain A.
3.40.50.300
Class: Alpha Beta
Architecture: 3-Layer(aba) Sandwich
Topology: Rossmann fold
Homology: P-loop containing nucleotide triphosphate hydrolases
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
The deposited structure of PDB entry 1ixz contains 1 copy of CATH domain 3.40.50.300 (Rossmann fold) in ATP-dependent zinc metalloprotease FtsH. Showing 1 copy in chain A.
SCOP SCOP annotation
81269
Class: Alpha and beta proteins (a/b)
Fold: P-loop containing nucleoside triphosphate hydrolases
Superfamily: P-loop containing nucleoside triphosphate hydrolases
Occurring in:
  1. ATP-dependent zinc metalloprotease FtsH
The deposited structure of PDB entry 1ixz contains 1 copy of SCOP domain 81269 (Extended AAA-ATPase domain) in ATP-dependent zinc metalloprotease FtsH. Showing 1 copy in chain A.