› › Structure analysis

X-ray crystal structure of IRF-3 and its functional implications

X-ray diffraction
2.3Å resolution
PDB entry 1j2f coloured by chain, front view.
PDB entry 1j2f coloured by chain, side view.
PDB entry 1j2f coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Interferon regulatory factor 3
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 10976.96 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-172049
Assembly 2
Download    3D Visualisation
Assembly Name: Interferon regulatory factor 3
hide full assembly name
Multimeric state: monomeric
Accessible surface area: 11818.34 Å2
Buried surface area: 0.0 Å2
Dissociation area: 0 Å2
Dissociation energy (ΔGdiss): 0 kcal/mol
Dissociation entropy (TΔSdiss): 0 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-172049

Macromolecules

Interferon regulatory factor 3
Chains: A, B
Length: 258 amino acids
Theoretical weight: 28.38 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q14653 (Residues: 175-427; Coverage: 59%)
Gene name: IRF3
Pfam: Interferon-regulatory factor 3
InterPro:
CATH: Tumour Suppressor Smad4
SCOP: Interferon regulatory factor 3 (IRF3), transactivation domain
Interferon regulatory factor 3 in PDB entry 1j2f, assembly 1, front view.
Interferon regulatory factor 3 in PDB entry 1j2f, assembly 1, side view.
Interferon regulatory factor 3 in PDB entry 1j2f, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links