› 1jh3

Solution NMR

Solution structure of tyrosyl-tRNA synthetase C-terminal domain.

Released:
DOI: 10.2210/pdb1jh3/pdb
PDB entry 1jh3 coloured by chain, ensemble of 20 models, front view.
PDB entry 1jh3 coloured by chain, ensemble of 20 models, side view.
PDB entry 1jh3 coloured by chain, ensemble of 20 models, top view.
Source organism: Geobacillus stearothermophilus
Primary publication:
Structure and dynamics of the anticodon arm binding domain of Bacillus stearothermophilus Tyrosyl-tRNA synthetase.
Guijarro JI, Pintar A, Prochnicka-Chalufour A, Guez V, Gilquin B, Bedouelle H, Delepierre M
Structure 10 311-7 (2002)
PMID: 12005430

Function and Biology Details

Reaction catalysed: 
ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + L-tyrosyl-tRNA(Tyr)
Biochemical function:
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-133713 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
Tyrosine--tRNA ligase Chain: A
Molecule details ›
Chain: A
Length: 107 amino acids
Theoretical weight: 12 KDa
Source organism: Geobacillus stearothermophilus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P00952 (Residues: 321-419; Coverage: 24%)
Gene name: tyrS
Sequence domains: Tyrosine--tRNA ligase SYY-like C-terminal domain
Structure domains: RNA-binding S4 domain

Ligands and Environments

No bound ligands
No modified residues

Experiments and Validation Details

Entry percentile scores
Refinement method: torsion angle dynamics simulated annealing
Expression system: Escherichia coli BL21(DE3)

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Citations

1 review citation

Evolution of the tRNA(Tyr)/TyrRS aminoacylation systems.
Bonnefond et al. (2005)
10 other articles