Structure analysis

Human Kallikrein 6 (hK6) Active Form with benzamidine inhibitor

X-ray diffraction
1.75Å resolution
Source organism: Homo sapiens
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

Assemblies

Assembly 1 (preferred)
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Multimeric state: monomeric
Accessible surface area: 10248.95 Å2
Buried surface area: 435.46 Å2
Dissociation area: 186.15 Å2
Dissociation energy (ΔGdiss): -5.42 kcal/mol
Dissociation entropy (TΔSdiss): 1.63 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-187789

Macromolecules

Chain: A
Length: 223 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Spodoptera frugiperda
UniProt:
  • Canonical: Q92876 (Residues: 22-244; Coverage: 98%)
Gene names: KLK6, PRSS18, PRSS9
Pfam: Trypsin
InterPro:
CATH: Trypsin-like serine proteases
SCOP: Eukaryotic proteases

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