Structure analysis

CRYSTAL STRUCTURE OF MAP KINASE P38 COMPLEXED TO THE DOCKING SITE ON ITS ACTIVATOR MKK3B

X-ray diffraction
2.3Å resolution
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 17233.86 Å2
Buried surface area: 962.47 Å2
Dissociation area: 481.23 Å2
Dissociation energy (ΔGdiss): 4.28 kcal/mol
Dissociation entropy (TΔSdiss): 6.71 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-126711

Macromolecules

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Chain: B
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
  • Canonical: O09110 (Residues: 15-32; Coverage: 5%)
Gene names: Map2k3, Mkk3, Prkmk3

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