Assemblies
Assembly Name:
Mitogen-activated protein kinase 14 and Dual specificity mitogen-activated protein kinase kinase 3
Multimeric state:
hetero dimer
Accessible surface area:
17233.86 Å2
Buried surface area:
962.47 Å2
Dissociation area:
481.23
Å2
Dissociation energy (ΔGdiss):
4.28
kcal/mol
Dissociation entropy (TΔSdiss):
6.71
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-126711
Macromolecules
Chain: A
Length: 360 amino acids
Theoretical weight: 41.34 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
Pfam: Protein kinase domain
InterPro:
SCOP: Protein kinases, catalytic subunit
Length: 360 amino acids
Theoretical weight: 41.34 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
- Canonical: P47811 (Residues: 1-360; Coverage: 100%)
Pfam: Protein kinase domain
InterPro:
- Mitogen-activated protein kinase 14
- Protein kinase-like domain superfamily
- Mitogen-activated protein (MAP) kinase p38-like
- Protein kinase domain
- Protein kinase, ATP binding site
- Mitogen-activated protein (MAP) kinase, conserved site
SCOP: Protein kinases, catalytic subunit
Chain: B
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
Length: 18 amino acids
Theoretical weight: 2.07 KDa
Source organism: Mus musculus
Expression system: Not provided
UniProt:
- Canonical: O09110 (Residues: 15-32; Coverage: 5%)