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DEOXY HEMOGLOBIN (90% RELATIVE HUMIDITY)

X-ray diffraction
2.7Å resolution
PDB entry 1lfl coloured by chain, front view.
PDB entry 1lfl coloured by chain, side view.
PDB entry 1lfl coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
hetero tetramer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Hemoglobin HbA complex
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Multimeric state: hetero tetramer
Accessible surface area: 23562.55 Å2
Buried surface area: 11117.02 Å2
Dissociation area: 1,632.71 Å2
Dissociation energy (ΔGdiss): 3.36 kcal/mol
Dissociation entropy (TΔSdiss): 13.72 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-159519
Complex Portal ID: CPX-2158
Assembly 2
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Assembly Name: Hemoglobin HbA complex
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Multimeric state: hetero tetramer
Accessible surface area: 23615.89 Å2
Buried surface area: 11156.16 Å2
Dissociation area: 3,275.4 Å2
Dissociation energy (ΔGdiss): 8.55 kcal/mol
Dissociation entropy (TΔSdiss): 36.74 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-159519
Complex Portal ID: CPX-2158

Macromolecules

Hemoglobin subunit alpha
Chains: A, C, P, R
Length: 141 amino acids
Theoretical weight: 15.15 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P69905 (Residues: 2-142; Coverage: 99%)
Gene names: HBA1, HBA2
Pfam: Globin
InterPro:
CATH: Globins
SCOP: Globins
Hemoglobin subunit alpha in PDB entry 1lfl, assembly 1, front view.
Hemoglobin subunit alpha in PDB entry 1lfl, assembly 1, side view.
Hemoglobin subunit alpha in PDB entry 1lfl, assembly 1, top view.
PDBe-KB: UniProt Coverage View: P69905  
1141102030405060708090100110120130140
 
50100
UniProt
P69905
PRO_0000455882
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Interaction interfaces
Molecule details ›

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Hemoglobin subunit beta
Chains: B, D, Q, S
Length: 146 amino acids
Theoretical weight: 15.89 KDa
Source organism: Homo sapiens
UniProt:
  • Canonical: P68871 (Residues: 2-147; Coverage: 99%)
Gene name: HBB
Pfam: Globin
InterPro:
CATH: Globins
SCOP: Globins
Hemoglobin subunit beta in PDB entry 1lfl, assembly 1, front view.
Hemoglobin subunit beta in PDB entry 1lfl, assembly 1, side view.
Hemoglobin subunit beta in PDB entry 1lfl, assembly 1, top view.
PDBe-KB: UniProt Coverage View: P68871  
114620406080100120140
 
50100
UniProt
P68871
PRO_0000296641
PRO_0000424226
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Ligand binding sites
Interaction interfaces
Molecule details ›

Search similar proteins

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