› › Structure analysis

HEAT-LABILE ENTEROTOXIN DOUBLE MUTANT N40C/G166C

X-ray diffraction
2Å resolution
PDB entry 1lt3 coloured by chain, front view.
PDB entry 1lt3 coloured by chain, side view.
PDB entry 1lt3 coloured by chain, top view.
Source organism: Escherichia coli
Assembly composition:
hetero hexamer (preferred)
Entry contents: 2 distinct polypeptide molecules

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Heat-labile enterotoxin
hide full assembly name
Multimeric state: hetero hexamer
Accessible surface area: 27968.03 Å2
Buried surface area: 20667.31 Å2
Dissociation area: 2,172.63 Å2
Dissociation energy (ΔGdiss): 0.29 kcal/mol
Dissociation entropy (TΔSdiss): 12.88 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-139158

Macromolecules

Heat-labile enterotoxin B chain
Chains: D, E, F, G, H
Length: 103 amino acids
Theoretical weight: 11.81 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P32890 (Residues: 22-124; Coverage: 100%)
Gene names: eltB, ltpB
Pfam: Heat-labile enterotoxin beta chain
InterPro:
CATH: OB fold (Dihydrolipoamide Acetyltransferase, E2P)
SCOP: Bacterial AB5 toxins, B-subunits
Heat-labile enterotoxin B chain in PDB entry 1lt3, assembly 1, front view.
Heat-labile enterotoxin B chain in PDB entry 1lt3, assembly 1, side view.
Heat-labile enterotoxin B chain in PDB entry 1lt3, assembly 1, top view.
Molecule details ›

Search similar proteins

Heat-labile enterotoxin A chain
Chain: A
Length: 240 amino acids
Theoretical weight: 27.89 KDa
Source organism: Escherichia coli
Expression system: Escherichia coli
UniProt:
  • Canonical: P06717 (Residues: 19-258; Coverage: 100%)
Gene names: eltA, ltpA
Pfam: Heat-labile enterotoxin alpha chain
InterPro: Heat-labile enterotoxin, A chain
CATH: Heat-Labile Enterotoxin, subunit A
SCOP: ADP-ribosylating toxins
Heat-labile enterotoxin A chain in PDB entry 1lt3, assembly 1, front view.
Heat-labile enterotoxin A chain in PDB entry 1lt3, assembly 1, side view.
Heat-labile enterotoxin A chain in PDB entry 1lt3, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links