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Multiple Methionine Substitutions are Tolerated in T4 Lysozyme and have Coupled Effects on Folding and Stability

X-ray diffraction
2.1Å resolution
PDB entry 1lwk coloured by chain, front view.
PDB entry 1lwk coloured by chain, side view.
PDB entry 1lwk coloured by chain, top view.
Source organism: Escherichia virus T4
Assembly composition:
monomeric (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Endolysin
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Multimeric state: monomeric
PDBe Complex ID: PDB-CPX-133020

Macromolecules

Endolysin
Chain: A
Length: 164 amino acids
Theoretical weight: 19.54 KDa
Source organism: Escherichia virus T4
Expression system: Escherichia coli
UniProt:
  • Canonical: P00720 (Residues: 1-164; Coverage: 100%)
Gene name: E
Pfam: Phage lysozyme
InterPro:
CATH: Lysozyme
SCOP: Phage lysozyme
Endolysin in PDB entry 1lwk, assembly 1, front view.
Endolysin in PDB entry 1lwk, assembly 1, side view.
Endolysin in PDB entry 1lwk, assembly 1, top view.
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