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NF-kappaB p65 subunit dimerization domain homodimer

X-ray diffraction
1.8Å resolution
PDB entry 1my5 coloured by chain, front view.
PDB entry 1my5 coloured by chain, side view.
PDB entry 1my5 coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
homo dimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Transcription factor p65
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Multimeric state: homo dimer
Accessible surface area: 11348.21 Å2
Buried surface area: 1291.44 Å2
Dissociation area: 645.72 Å2
Dissociation energy (ΔGdiss): -2.38 kcal/mol
Dissociation entropy (TΔSdiss): 11.12 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-170005

Macromolecules

Transcription factor p65
Chains: A, B
Length: 114 amino acids
Theoretical weight: 13.2 KDa
Source organism: Mus musculus
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: Q04207 (Residues: 191-304; Coverage: 21%)
Gene names: Nfkb3, Rela
Pfam: Rel homology dimerisation domain
InterPro:
CATH: Immunoglobulins
SCOP: NF-kappa-B/REL/DORSAL transcription factors, C-terminal domain
Transcription factor p65 in PDB entry 1my5, assembly 1, front view.
Transcription factor p65 in PDB entry 1my5, assembly 1, side view.
Transcription factor p65 in PDB entry 1my5, assembly 1, top view.
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