› 1na0

X-ray diffraction
1.6Å resolution

Design of Stable alpha-Helical Arrays from an Idealized TPR Motif

Released:
DOI: 10.2210/pdb1na0/pdb
PDB entry 1na0 coloured by chain, front view.
PDB entry 1na0 coloured by chain, side view.
PDB entry 1na0 coloured by chain, top view.
Source organism: unidentified
Primary publication:
Design of stable alpha-helical arrays from an idealized TPR motif.
Main ER, Xiong Y, Cocco MJ, D'Andrea L, Regan L
Structure 11 497-508 (2003)
PMID: 12737816

Function and Biology Details

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned
Sequence domains:
Structure domain:

Structure analysis Details

Assembly composition:
monomeric (preferred)
Assembly name:
PDBe Complex ID:
PDB-CPX-162337 (preferred)
Entry contents:
1 distinct polypeptide molecule
Macromolecule:
designed protein CTPR3 Chains: A, B
Molecule details ›
Chains: A, B
Length: 125 amino acids
Theoretical weight: 14.37 KDa
Source organism: unidentified
Expression system: Escherichia coli
Structure domains: Tetratricopeptide repeat domain

Ligands and Environments

6 bound ligands:
Ligand PB 5 x PB
Ligand ACT 1 x ACT
Ligand CL 1 x CL
Ligand NA 2 x NA
Ligand MG 1 x MG
Ligand IPT 2 x IPT
No modified residues

Experiments and Validation Details

Entry percentile scores
X-ray source: NSLS BEAMLINE X25
Spacegroup: C2
Unit cell:
a: 102.734Å b: 46.56Å c: 52.517Å
α: 90° β: 99.11° γ: 90°
R-values:
R R work R free
0.186 0.183 0.216
Expression system: Escherichia coli

Quick links

Citations

19 review citations

Engineering novel binding proteins from nonimmunoglobulin domains.
Binz et al. (2005)
18 more

32 mentions without citation

Ligand binding by repeat proteins: natural and designed.
Grove et al. (2008)
31 more