Function and Biology

Connexin 43 Carboxyl Terminal Domain

Source organism: Rattus norvegicus
Biochemical function: transmembrane transporter activity
Biological process: heart development
Cellular component: connexin complex

GO terms

Biochemical function:
Biological process:
Cellular component:

Sequence family

Pfam Protein family (Pfam)
PF03508
Domain description: Gap junction alpha-1 protein (Cx43)
Occurring in:
  1. Gap junction alpha-1 protein
The deposited structure of PDB entry 1r5s contains 1 copy of Pfam domain PF03508 (Gap junction alpha-1 protein (Cx43)) in Gap junction alpha-1 protein. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR002261
Domain description: Gap junction alpha-1 protein (Cx43)
Occurring in:
  1. Gap junction alpha-1 protein
IPR035091
Domain description: Gap junction alpha-1 protein (Cx43), alpha helix domain superfamily
Occurring in:
  1. Gap junction alpha-1 protein
IPR013124
Domain description: Gap junction alpha-1 protein (Cx43), C-terminal
Occurring in:
  1. Gap junction alpha-1 protein
IPR034634
Domain description: Connexin, C-terminal
Occurring in:
  1. Gap junction alpha-1 protein

Structure domain

CATH CATH domain
1.20.5.1130
Class: Mainly Alpha
Architecture: Up-down Bundle
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Connexin43
Occurring in:
  1. Gap junction alpha-1 protein
The deposited structure of PDB entry 1r5s contains 1 copy of CATH domain 1.20.5.1130 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Gap junction alpha-1 protein. Showing 1 copy in chain A.
SCOP SCOP annotation
118221
Class: Membrane and cell surface proteins and peptides
Fold: Connexin43
Superfamily: Connexin43
Occurring in:
  1. Gap junction alpha-1 protein
The deposited structure of PDB entry 1r5s contains 1 copy of SCOP domain 118221 (Connexin43) in Gap junction alpha-1 protein. Showing 1 copy in chain A.