Structure analysis

CRYSTAL STRUCTURE OF CIBOULOT IN COMPLEX WITH SKELETAL ACTIN

X-ray diffraction
2.5Å resolution
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
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Multimeric state: hetero dimer
Accessible surface area: 16755.45 Å2
Buried surface area: 3629.92 Å2
Dissociation area: 857.79 Å2
Dissociation energy (ΔGdiss): 5.89 kcal/mol
Dissociation entropy (TΔSdiss): 9.61 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-132189

Macromolecules

Chain: A
Length: 377 amino acids
Theoretical weight: 42.1 KDa
Source organism: Oryctolagus cuniculus
UniProt:
  • Canonical: P68135 (Residues: 1-377; Coverage: 100%)
Gene names: ACTA, ACTA1
Pfam: Actin
InterPro:
CATH:
SCOP: Actin/HSP70
PDBe-KB: UniProt Coverage View: P68135  
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Chain: B
Length: 25 amino acids
Theoretical weight: 2.79 KDa
Source organism: Drosophila melanogaster
Expression system: Escherichia coli
UniProt:
  • Canonical: O97428 (Residues: 10-34; Coverage: 19%)
Gene names: CG4944, Dmel\CG4944, Dmel_CG4944, EG0007-11, EG:EG0007.11, cib
Pfam: Thymosin beta-4 family
InterPro: Beta-thymosin
SCOP: Actin-binding peptides
PDBe-KB: UniProt Coverage View: O97428  
12524681012141618202224
 
1020DLPKVAENLKSQLEGFNQDKLKNAS
UniProt
O97428
Chains
Domains
Secondary structure
Flexibility predictions
Early folding residue predictions
Interaction interfaces
Sequence conservation

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