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ATOMIC STRUCTURE OF A THERMOSTABLE SUBDOMAIN OF HIV-1 GP41

X-ray diffraction
2.4Å resolution
PDB entry 1szt coloured by chain, front view.
PDB entry 1szt coloured by chain, side view.
PDB entry 1szt coloured by chain, top view.
Source organism: Human immunodeficiency virus 1
Assembly composition:
homo trimer (preferred)
Entry contents: 1 distinct polypeptide molecule

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Assemblies

Assembly 1 (preferred)
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Assembly Name: Envelope glycoprotein
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Multimeric state: homo trimer
Accessible surface area: 10838.64 Å2
Buried surface area: 6687.36 Å2
Dissociation area: 3,343.68 Å2
Dissociation energy (ΔGdiss): 37.79 kcal/mol
Dissociation entropy (TΔSdiss): 22.64 kcal/mol
Symmetry number: 3
PDBe Complex ID: PDB-CPX-174570

Macromolecules

Envelope glycoprotein
Chain: A
Length: 68 amino acids
Theoretical weight: 7.88 KDa
Source organism: Human immunodeficiency virus 1
Expression system: Escherichia coli
UniProt:
  • Canonical: Q3I1N2 (Residues: 15-48; Coverage: 57%)
Gene name: env
Pfam: Retroviral envelope protein
CATH: Helix Hairpins
SCOP: Virus ectodomain
Envelope glycoprotein in PDB entry 1szt, assembly 1, front view.
Envelope glycoprotein in PDB entry 1szt, assembly 1, side view.
Envelope glycoprotein in PDB entry 1szt, assembly 1, top view.
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