Assemblies
Multimeric state:
hetero dimer
Accessible surface area:
11241.31 Å2
Buried surface area:
983.94 Å2
Dissociation area:
491.97
Å2
Dissociation energy (ΔGdiss):
2.46
kcal/mol
Dissociation entropy (TΔSdiss):
6.99
kcal/mol
Symmetry number:
1
PDBe Complex ID:
PDB-CPX-153641
Macromolecules
Chain: A
Length: 214 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
Pfam: BRCA1 C Terminus (BRCT) domain
InterPro:
SCOP: BRCT domain
Length: 214 amino acids
Theoretical weight: 24.53 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21
UniProt:
- Canonical:
P38398 (Residues: 1646-1859; Coverage: 12%)
Pfam: BRCA1 C Terminus (BRCT) domain
InterPro:
- BRCT domain
- BRCA1-associated
- BRCT domain superfamily
- Breast cancer type 1 susceptibility protein (BRCA1)
SCOP: BRCT domain
Chain: B
Length: 8 amino acids
Theoretical weight: 962 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
Length: 8 amino acids
Theoretical weight: 962 Da
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
- Canonical:
Q9BX63 (Residues: 988-995; Coverage: 1%)