› › Structure analysis

Human cytosolic acetoacetyl-CoA thiolase

X-ray diffraction
2.26Å resolution
PDB entry 1wl5 coloured by chain, front view.
PDB entry 1wl5 coloured by chain, side view.
PDB entry 1wl5 coloured by chain, top view.
Source organism: Homo sapiens
Assembly composition:
homo tetramer (preferred)
Entry contents: 1 distinct polypeptide molecule

Quick links

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Assembly Name: Acetyl-CoA acetyltransferase, cytosolic
hide full assembly name
Multimeric state: homo tetramer
Accessible surface area: 49848.84 Å2
Buried surface area: 18257.05 Å2
Dissociation area: 1,843.29 Å2
Dissociation energy (ΔGdiss): 23.94 kcal/mol
Dissociation entropy (TΔSdiss): 15.15 kcal/mol
Symmetry number: 4
PDBe Complex ID: PDB-CPX-189774

Macromolecules

Acetyl-CoA acetyltransferase, cytosolic
Chain: A
Length: 397 amino acids
Theoretical weight: 41.41 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli
UniProt:
  • Canonical: Q9BWD1 (Residues: 1-397; Coverage: 100%)
Gene names: ACAT2, ACTL
Pfam:
InterPro:
CATH: Peroxisomal Thiolase; Chain A, domain 1
Acetyl-CoA acetyltransferase, cytosolic in PDB entry 1wl5, assembly 1, front view.
Acetyl-CoA acetyltransferase, cytosolic in PDB entry 1wl5, assembly 1, side view.
Acetyl-CoA acetyltransferase, cytosolic in PDB entry 1wl5, assembly 1, top view.
Molecule details ›

Search similar proteins

Quick links