Structure analysis

Crystal structure of a ternary complex of the methyltransferase SET9 (also known as SET7/9) with a P53 peptide and SAH

X-ray diffraction
1.75Å resolution
Source organism: Homo sapiens
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero dimer
Accessible surface area: 12821.2 Å2
Buried surface area: 1220.64 Å2
Dissociation area: 610.32 Å2
Dissociation energy (ΔGdiss): 4.96 kcal/mol
Dissociation entropy (TΔSdiss): 6.23 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138121
Assembly 2
Download    3D Visualisation
Multimeric state: hetero dimer
Accessible surface area: 12801.92 Å2
Buried surface area: 1214.94 Å2
Dissociation area: 607.47 Å2
Dissociation energy (ΔGdiss): 3.85 kcal/mol
Dissociation entropy (TΔSdiss): 6.25 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-138121

Macromolecules

Search similar proteins

Chains: B, F
Length: 10 amino acids
Theoretical weight: 1.16 KDa
Source organism: Homo sapiens
Expression system: Not provided
UniProt:
  • Canonical: P04637 (Residues: 369-377; Coverage: 2%)
Gene names: P53, TP53

Search similar proteins