Structure analysis

THE YEAST ACTIN VAL 159 ASN MUTANT COMPLEX WITH HUMAN GELSOLIN SEGMENT 1.

X-ray diffraction
2.1Å resolution
Assemblies composition:
hetero dimer (preferred)
hetero tetramer
Entry contents: 2 distinct polypeptide molecules

Assemblies

Assembly 1 (preferred)
Download    3D Visualisation
Multimeric state: hetero dimer
Accessible surface area: 20887.26 Å2
Buried surface area: 3430.17 Å2
Dissociation area: 1,002.11 Å2
Dissociation energy (ΔGdiss): 5.2 kcal/mol
Dissociation entropy (TΔSdiss): 12.14 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-139013
Assembly 2
Download    3D Visualisation
Multimeric state: hetero tetramer
Accessible surface area: 39395.35 Å2
Buried surface area: 9246.7 Å2
Dissociation area: 2,007.14 Å2
Dissociation energy (ΔGdiss): 9.82 kcal/mol
Dissociation entropy (TΔSdiss): 24.87 kcal/mol
Symmetry number: 2
PDBe Complex ID: PDB-CPX-139021

Macromolecules

Chain: A
Length: 375 amino acids
Theoretical weight: 41.75 KDa
Source organism: Saccharomyces cerevisiae
UniProt:
  • Canonical: P60010 (Residues: 1-375; Coverage: 100%)
Gene names: ABY1, ACT1, END7, YFL039C
Pfam: Actin
InterPro:
CATH:
SCOP: Actin/HSP70

Search similar proteins

Chain: G
Length: 125 amino acids
Theoretical weight: 14.07 KDa
Source organism: Homo sapiens
Expression system: Escherichia coli BL21(DE3)
UniProt:
  • Canonical: P06396 (Residues: 52-176; Coverage: 17%)
Gene name: GSN
Pfam: Gelsolin repeat
InterPro:
CATH: Severin
SCOP: Gelsolin-like

Search similar proteins