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Structure of yeast oxysterol binding protein Osh4 in complex with ergosterol

Source organism: Saccharomyces cerevisiae
Biochemical function: sterol transfer activity
Biological process: ER to Golgi ceramide transport
Cellular component: membrane

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GO terms

Sequence family

Pfam Protein family (Pfam)
PF01237
Domain description: Oxysterol-binding protein
Occurring in:
  1. Oxysterol-binding protein homolog 4
The deposited structure of PDB entry 1zhz contains 1 copy of Pfam domain PF01237 (Oxysterol-binding protein) in Oxysterol-binding protein homolog 4. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000648
Domain description: Oxysterol-binding protein
Occurring in:
  1. Oxysterol-binding protein homolog 4
IPR018494
Domain description: Oxysterol-binding protein, conserved site
Occurring in:
  1. Oxysterol-binding protein homolog 4
IPR037239
Domain description: Oxysterol-binding protein superfamily
Occurring in:
  1. Oxysterol-binding protein homolog 4

Structure domains

CATH CATH domains
3.30.70.3490
Class: Alpha Beta
Architecture: 2-Layer Sandwich
Topology: Alpha-Beta Plaits
Homology: Alpha-Beta Plaits
Occurring in:
  1. Oxysterol-binding protein homolog 4
The deposited structure of PDB entry 1zhz contains 1 copy of CATH domain 3.30.70.3490 (Alpha-Beta Plaits) in Oxysterol-binding protein homolog 4. Showing 1 copy in chain A.
2.40.160.120
Class: Mainly Beta
Architecture: Beta Barrel
Topology: Porin
Homology: Porin
Occurring in:
  1. Oxysterol-binding protein homolog 4
The deposited structure of PDB entry 1zhz contains 1 copy of CATH domain 2.40.160.120 (Porin) in Oxysterol-binding protein homolog 4. Showing 1 copy in chain A.
1.10.287.2720
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Helix Hairpins
Homology: Helix Hairpins
Occurring in:
  1. Oxysterol-binding protein homolog 4
The deposited structure of PDB entry 1zhz contains 1 copy of CATH domain 1.10.287.2720 (Helix Hairpins) in Oxysterol-binding protein homolog 4. Showing 1 copy in chain A.
6.10.250.1430
Class: Special
Architecture: Helix non-globular
Topology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Homology: Single alpha-helices involved in coiled-coils or other helix-helix interfaces
Occurring in:
  1. Oxysterol-binding protein homolog 4
The deposited structure of PDB entry 1zhz contains 1 copy of CATH domain 6.10.250.1430 (Single alpha-helices involved in coiled-coils or other helix-helix interfaces) in Oxysterol-binding protein homolog 4. Showing 1 copy in chain A.
SCOP SCOP annotation
144001
Class: Alpha and beta proteins (a+b)
Fold: Oxysterol-binding protein-like
Superfamily: Oxysterol-binding protein-like
Occurring in:
  1. Oxysterol-binding protein homolog 4
The deposited structure of PDB entry 1zhz contains 1 copy of SCOP domain 144001 (Oxysterol-binding protein) in Oxysterol-binding protein homolog 4. Showing 1 copy in chain A.

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