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CATALYTIC ANTIBODY 5C8, FAB-HAPTEN COMPLEX

X-ray diffraction
2Å resolution
PDB entry 25c8 coloured by chain, front view.
PDB entry 25c8 coloured by chain, side view.
PDB entry 25c8 coloured by chain, top view.
Source organism: Mus musculus
Assembly composition:
hetero dimer (preferred)
Entry contents: 2 distinct polypeptide molecules

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Assemblies

Assembly 1 (preferred)
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Assembly Name: IG-light kappa chain and IG-heavy chain
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Multimeric state: hetero dimer
Accessible surface area: 19197.39 Å2
Buried surface area: 4084.06 Å2
Dissociation area: 1,785.05 Å2
Dissociation energy (ΔGdiss): 9.96 kcal/mol
Dissociation entropy (TΔSdiss): 13.15 kcal/mol
Symmetry number: 1
PDBe Complex ID: PDB-CPX-134674

Macromolecules

Immunoglobulin kappa constant
Chain: L
Length: 212 amino acids
Theoretical weight: 23.15 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01837 (Residues: 1-104; Coverage: 97%)
Gene name: Igkc
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Immunoglobulin kappa constant in PDB entry 25c8, assembly 1, front view.
Immunoglobulin kappa constant in PDB entry 25c8, assembly 1, side view.
Immunoglobulin kappa constant in PDB entry 25c8, assembly 1, top view.
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Ig gamma-1 chain C region, membrane-bound form
Chain: H
Length: 217 amino acids
Theoretical weight: 23.1 KDa
Source organism: Mus musculus
UniProt:
  • Canonical: P01869 (Residues: 1-98; Coverage: 25%)
Gene names: Igh-4, Ighg1
Pfam: Immunoglobulin C1-set domain
InterPro:
CATH: Immunoglobulins
SCOP:
Ig gamma-1 chain C region, membrane-bound form in PDB entry 25c8, assembly 1, front view.
Ig gamma-1 chain C region, membrane-bound form in PDB entry 25c8, assembly 1, side view.
Ig gamma-1 chain C region, membrane-bound form in PDB entry 25c8, assembly 1, top view.
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