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The solution structure of the Ki67FHA/hNIFK(226-269)3P complex

Source organism: Homo sapiens
Biochemical function: not assigned
Biological process: not assigned
Cellular component: not assigned

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GO terms

Biochemical function:
  • not assigned
Biological process:
  • not assigned
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF12196
Domain description: FHA Ki67 binding domain of hNIFK
Occurring in:
  1. MKI67 FHA domain-interacting nucleolar phosphoprotein
The deposited structure of PDB entry 2aff contains 1 copy of Pfam domain PF12196 (FHA Ki67 binding domain of hNIFK) in MKI67 FHA domain-interacting nucleolar phosphoprotein. Showing 1 copy in chain B.

PF00498
Domain description: FHA domain
Occurring in:
  1. Proliferation marker protein Ki-67
The deposited structure of PDB entry 2aff contains 1 copy of Pfam domain PF00498 (FHA domain) in Proliferation marker protein Ki-67. Showing 1 copy in chain A.

InterPro InterPro annotations
IPR000253
Domain description: Forkhead-associated (FHA) domain
Occurring in:
  1. Proliferation marker protein Ki-67
IPR021043
Domain description: MKI67 FHA domain-interacting nucleolar phosphoprotein, FHA Ki67 binding
Occurring in:
  1. MKI67 FHA domain-interacting nucleolar phosphoprotein
IPR008984
Domain description: SMAD/FHA domain superfamily
Occurring in:
  1. Proliferation marker protein Ki-67

Structure domain

CATH CATH domain
2.60.200.20
Class: Mainly Beta
Architecture: Sandwich
Topology: Tumour Suppressor Smad4
Homology: Tumour Suppressor Smad4
Occurring in:
  1. Proliferation marker protein Ki-67
The deposited structure of PDB entry 2aff contains 1 copy of CATH domain 2.60.200.20 (Tumour Suppressor Smad4) in Proliferation marker protein Ki-67. Showing 1 copy in chain A.
SCOP SCOP annotation
49885
Class: All beta proteins
Fold: SMAD/FHA domain
Superfamily: SMAD/FHA domain
Occurring in:
  1. Proliferation marker protein Ki-67
The deposited structure of PDB entry 2aff contains 1 copy of SCOP domain 49885 (FHA domain) in Proliferation marker protein Ki-67. Showing 1 copy in chain A.

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