› › Function and Biology

Crystal structure of the dimeric regulatory domain of mouse diaphaneous-related formin (DRF), mDia1

Source organism: Mus musculus
Biochemical function: small GTPase binding
Biological process: actin cytoskeleton organization
Cellular component: not assigned

Quick links

GO terms

Biochemical function:
Biological process:
Cellular component:
  • not assigned

Sequence families

Pfam Protein families (Pfam)
PF06367
Domain description: Diaphanous FH3 Domain
Occurring in:
  1. Protein diaphanous homolog 1
The deposited structure of PDB entry 2bnx contains 2 copies of Pfam domain PF06367 (Diaphanous FH3 Domain) in Protein diaphanous homolog 1. Showing 1 copy in chain B.

PF06371
Domain description: Diaphanous GTPase-binding Domain
Occurring in:
  1. Protein diaphanous homolog 1
The deposited structure of PDB entry 2bnx contains 2 copies of Pfam domain PF06371 (Diaphanous GTPase-binding Domain) in Protein diaphanous homolog 1. Showing 1 copy in chain B.

InterPro InterPro annotations
IPR010472
Domain description: Formin, FH3 domain
Occurring in:
  1. Protein diaphanous homolog 1
IPR010473
Domain description: Formin, GTPase-binding domain
Occurring in:
  1. Protein diaphanous homolog 1
IPR016024
Domain description: Armadillo-type fold
Occurring in:
  1. Protein diaphanous homolog 1
IPR011989
Domain description: Armadillo-like helical
Occurring in:
  1. Protein diaphanous homolog 1
IPR014768
Domain description: Rho GTPase-binding/formin homology 3 (GBD/FH3) domain
Occurring in:
  1. Protein diaphanous homolog 1

Structure domains

CATH CATH domains
1.10.238.150
Class: Mainly Alpha
Architecture: Orthogonal Bundle
Topology: Recoverin; domain 1
Homology: Formin, FH3 diaphanous domain
Occurring in:
  1. Protein diaphanous homolog 1
The deposited structure of PDB entry 2bnx contains 2 copies of CATH domain 1.10.238.150 (Recoverin; domain 1) in Protein diaphanous homolog 1. Showing 1 copy in chain B.
1.25.10.10
Class: Mainly Alpha
Architecture: Alpha Horseshoe
Topology: Leucine-rich Repeat Variant
Homology: Leucine-rich Repeat Variant
Occurring in:
  1. Protein diaphanous homolog 1
The deposited structure of PDB entry 2bnx contains 2 copies of CATH domain 1.25.10.10 (Leucine-rich Repeat Variant) in Protein diaphanous homolog 1. Showing 1 copy in chain B.
SCOP SCOP annotation
140830
Class: All alpha proteins
Fold: alpha-alpha superhelix
Superfamily: ARM repeat
Occurring in:
  1. Protein diaphanous homolog 1
The deposited structure of PDB entry 2bnx contains 2 copies of SCOP domain 140830 (Diap1 N-terninal region-like) in Protein diaphanous homolog 1. Showing 1 copy in chain B.

Quick links